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1

Effect of the proteolytic enzyme serrapeptase in patients with chronic airway disease

Seiichi NAKAMURA, Yasushi HASHIMOTO, Masashi MIKAMI, Eiichi YAMANAKA, Tomoyuki SOMA, Mitsunori HINO, Arata AZUMA, Shoji KUDOH

Journal:

Year:

2003

Language:

english

File:

PDF, 73 KB

english, 2003

2

Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease

Distler, Oliver, Highland, Kristin B., Gahlemann, Martina, Azuma, Arata, Fischer, Aryeh, Mayes, Maureen D., Raghu, Ganesh, Sauter, Wiebke, Girard, Mannaig, Alves, Margarida, Clerisme-Beaty, Emmanuelle

Journal:

New England Journal of Medicine

Year:

2019

Language:

english

File:

PDF, 268 KB

english, 2019

3

Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis

Richeldi, Luca, du Bois, Roland M., Raghu, Ganesh, Azuma, Arata, Brown, Kevin K., Costabel, Ulrich, Cottin, Vincent, Flaherty, Kevin R., Hansell, David M., Inoue, Yoshikazu, Kim, Dong Soon, Kolb, Mart

Journal:

New England Journal of Medicine

Year:

2014

Language:

english

File:

PDF, 565 KB

english, 2014

4

[Milestones in Drug Therapy] Treatment of Cystic Fibrosis and Other Rare Lung Diseases || Anti-Inflammatory Therapies for Cystic Fibrosis

Azuma, Arata, Schechter, Michael S.

Year:

2017

Language:

english

File:

PDF, 163 KB

english, 2017

5

Japanese guideline for the treatment of idiopathic pulmonary fibrosis

Homma, Sakae, Bando, Masashi, Azuma, Arata, Sakamoto, Susumu, Sugino, Keishi, Ishii, Yoshiki, Izumi, Shinyu, Inase, Naohiko, Inoue, Yoshikazu, Ebina, Masahito, Ogura, Takashi, Kishi, Kazuma, Kishaba,

Journal:

Respiratory Investigation

Year:

2018

Language:

english

File:

PDF, 877 KB

english, 2018

6

A case of severe pneumonitis with alveolar hemorrhage associated with herbal medicines

Omori, Miwako, Saito, Yoshinobu, Miura, Yukiko, Tanaka, Toru, Kashiwada, Takeru, Atsumi, Kenichiro, Hayashi, Hiroki, Minegishi, Yuji, Fujita, Kazue, Azuma, Arata, Seike, Masahiro, Gemma, Akihiko

Journal:

Journal of Nippon Medical School

Year:

2019

Language:

english

File:

PDF, 326 KB

english, 2019

7

JCS 2016 Guideline on Diagnosis and Treatment of Cardiac Sarcoidosis　― Digest Version ―

Terasaki, Fumio, Azuma, Arata, Anzai, Toshihisa, Ishizaka, Nobukazu, Ishida, Yoshio, Isobe, Mitsuaki, Inomata, Takayuki, Ishibashi-Ueda, Hatsue, Eishi, Yoshinobu, Kitakaze, Masafumi, Kusano, Kengo, Sa

Journal:

Circulation Journal

Year:

2019

File:

PDF, 13.56 MB

2019

8

Exploratory analysis of a phase III trial of pirfenidone identifies a subpopulation of patients with idiopathic pulmonary fibrosis as benefiting from treatment

Arata Azuma, Yoshio Taguchi, Takashi Ogura, Masahito Ebina, Hiroyuki Taniguchi, Yasuhiro Kondoh, Moritaka Suga, Hiroki Takahashi, Koichiro Nakata, Atsuhiko Sato, Shoji Kudoh, Toshihiro Nukiwa, Pirfeni

Journal:

Respiratory Research

Year:

2011

Language:

english

File:

PDF, 459 KB

english, 2011

9

The clinical significance of 5% change in vital capacity in patients with idiopathic pulmonary fibrosis: extended analysis of the pirfenidone trial

Hiroyuki Taniguchi, Yasuhiro Kondoh, Masahito Ebina, Arata Azuma, Takashi Ogura, Yoshio Taguchi, Moritaka Suga, Hiroki Takahashi, Koichiro Nakata, Atsuhiko Sato, Yukihiko Sugiyama, Shoji Kudoh, Toshih

Journal:

Respiratory Research

Year:

2011

Language:

english

File:

PDF, 296 KB

english, 2011

10

Potentiation of long-term-cultured lymphokine-activated killer cell cytotoxicity against small-cell lung carcinoma by anti-CD3 x anti-(tumor-associated antigen) bispecific antibody

Arata Azuma, Hideo Yagita, Ko Okumura, Shoji Kudoh, Hisanobu Niitani

Journal:

Cancer Immunology, Immunotherapy

Year:

1994

Language:

english

File:

PDF, 501 KB

english, 1994

11

Hypercytokinemia with 2009 pandemic H1N1 (pH1N1) influenza successfully treated with polymyxin

Shinhiro Takeda, Ryo Munakata, Shinji Abe, Seiji Mii, Manabu Suzuki, Takeru Kashiwada, Arata Azuma, Takeshi Yamamoto, Akihiko Gemma, Keiji Tanaka

Journal:

Intensive Care Medicine

Year:

2010

Language:

english

File:

PDF, 188 KB

english, 2010

12

Molecular cloning of two novel mucin-like genes in the disease-susceptibility locus for diffuse panbronchiolitis

Minako Hijikata, Ikumi Matsushita, Goh Tanaka, Tomoko Tsuchiya, Hideyuki Ito, Katsushi Tokunaga, Jun Ohashi, Sakae Homma, Yoichiro Kobashi, Yoshio Taguchi, Arata Azuma, Shoji Kudoh, Naoto Keicho

Journal:

Year:

2011

Language:

english

File:

PDF, 736 KB

english, 2011

13

Association of diffuse panbronchiolitis with microsatellite polymorphism of the human interleukin 8 (IL-8) gene

M. Emi, Naoto Keicho, Katsushi Tokunaga, Harumi Katsumata, Sachi Souma, Koichiro Nakata, Yoshio Taguchi, Nobuya Ohishi, Arata Azuma, Shoji Kudoh

Journal:

Journal of Human Genetics

Year:

1999

Language:

english

File:

PDF, 50 KB

english, 1999

14

Microbial substitution ofMycobacterium avium-intracellularetoMycobacterium abscessusduring clinical course

Takahito Nei, Takefumi Saitoh, Kouzo Morimoto, Kohichi Watanabe, Kenji Hayashihara, Arata Azuma, Shoji Kudoh

Journal:

Journal of Infection and Chemotherapy

Year:

2007

Language:

english

File:

PDF, 254 KB

english, 2007

15

Leflunomide-related lung injury in patients with rheumatoid arthritis: imaging features

Fumikazu Sakai, Satoshi Noma, Yasuyuki Kurihara, Hidehiro Yamada, Arata Azuma, Shoji Kudoh, Youichi Ichikawa

Journal:

Modern Rheumatology

Year:

2005

Language:

english

File:

PDF, 331 KB

english, 2005

16

Letters to the Editor

Arata AZUMA, SHOJI KUDOH, Tsukasa SEYA

Journal:

Scandinavian Journal of Immunology

Year:

1996

Language:

english

File:

PDF, 46 KB

english, 1996

17

Case-control study of medical history and idiopathic pulmonary fibrosis in Japan

Yoshihiro MIYAKE, Satoshi SASAKI, Tetsuji YOKOYAMA, Kingo CHIDA, Arata AZUMA, Takafumi SUDA, Shoji KUDOH, Naomasa SAKAMOTO, Kazushi OKAMOTO, Gen KOBASHI, Masakazu WASHIO, Yutaka INABA, Heizo TANAKA, T

Journal:

Year:

2005

Language:

english

File:

PDF, 71 KB

english, 2005

18

Diffuse panbronchiolitis in East Asia

Arata AZUMA, Shoji KUDOH

Journal:

Year:

2006

Language:

english

File:

PDF, 627 KB

english, 2006

19

Differences in the clinical characteristics of Pneumocystis jirovecii pneumonia in immunocompromized patients with and without HIV infection

Tatsuji ENOMOTO, Arata AZUMA, Ayumi KOHNO, Kazuyo KANEKO, Hitoshi SAITO, Minako KAMETAKA, Jiro USUKI, Akihiko GEMMA, Shoji KUDOH, Seiichi NAKAMURA

Journal:

Year:

2010

Language:

english

File:

PDF, 140 KB

english, 2010

20

INHIBITORY EFFECTS OF MACROLIDE ANTIBIOTICS ON EXACERBATIONS AND HOSPITALIZATION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN JAPAN: A RETROSPECTIVE MULTICENTER ANALYSIS

Mutsuo Yamaya, Arata Azuma, Hiroshi Tanaka, Hajime Takizawa, Kingo Chida, Yoshio Taguchi, Keiichi Mikasa, Junichi Kadota, Shoji Kudoh

Journal:

Journal of the American Geriatrics Society

Year:

2008

Language:

english

File:

PDF, 72 KB

english, 2008

21

Heat shock protein 70 protects against bleomycin-induced pulmonary fibrosis in mice

Ken-Ichiro Tanaka, Yuta Tanaka, Takushi Namba, Arata Azuma, Tohru Mizushima

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.01 MB

english, 2010

22

Repeated exposure to low-dose diesel exhaust after allergen challenge exaggerates asthmatic responses in mice

Aki Matsumoto, Kumiko Hiramatsu, Yingji Li, Arata Azuma, Shoji Kudoh, Hajime Takizawa, Isamu Sugawara

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 821 KB

english, 2006

23

Disruption of Nrf2 enhances susceptibility to airway inflammatory responses induced by low-dose diesel exhaust particles in mice

Ying Ji Li, Hajime Takizawa, Arata Azuma, Tadashi Kohyama, Yasuhiro Yamauchi, Satoru Takahashi, Masayuki Yamamoto, Tomoyuki Kawada, Shoji Kudoh, Isamu Sugawara

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 1.06 MB

english, 2008

24

Nrf2 is closely related to allergic airway inflammatory responses induced by low-dose diesel exhaust particles in mice

Ying Ji Li, Hajime Takizawa, Arata Azuma, Tadashi Kohyama, Yasuhiro Yamauchi, Satoru Takahashi, Masayuki Yamamoto, Tomoyuki Kawada, Shoji Kudoh, Isamu Sugawara

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 1.11 MB

english, 2010

25

Novel therapy for idiopathic pulmonary fibrosis—How to evaluate the efficacy?

Arata Azuma, Jiro Usuki

Journal:

Respiratory Medicine CME

Year:

2008

Language:

english

File:

PDF, 381 KB

english, 2008

26

Differential secretion of cytokines and adhesion molecules by HUVEC stimulated with low concentrations of bleomycin

Haruko Miyamoto, Isamu Sugawara, Arata Azuma, Yoshinobu Saito, Nobuoki Kohno, Shoji Kudoh

Journal:

Cellular Immunology

Year:

2002

Language:

english

File:

PDF, 360 KB

english, 2002

27

Efficacy of inhaled N-acetylcysteine monotherapy in patients with early stage idiopathic pulmonary fibrosis

SAKAE HOMMA, ARATA AZUMA, HIROYUKI TANIGUCHI, TAKASHI OGURA, YOSHIRO MOCHIDUKI, YUKIHIKO SUGIYAMA, KOICHIRO NAKATA, KUNIHIKO YOSHIMURA, MASAHIRO TAKEUCHI, SHOJI KUDOH, THE JAPAN NAC CLINICAL STUDY GRO

Journal:

Year:

2012

Language:

english

File:

PDF, 679 KB

english, 2012

28

α1,6-Fucosyltransferase (Fut8) is implicated in vulnerability to elastase-induced emphysema in mice and a possible non-invasive predictive marker for disease progression and exacerbations in chronic obstructive pulmonary disease (COPD)

Koichiro Kamio, Takayuki Yoshida, Congxiao Gao, Takeo Ishii, Fumi Ota, Takashi Motegi, Satoshi Kobayashi, Reiko Fujinawa, Kazuaki Ohtsubo, Shinobu Kitazume, Takashi Angata, Arata Azuma, Akihiko Gemma,

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 484 KB

english, 2012

29

Sequential changes of Legionella antigens and bacterial load in the lungs and urines of a mouse model of pneumonia

Yu Chen, Kazuhiro Tateda, Kazue Fujita, Toshiaki Ishii, Yoshikazu Ishii, Soichiro Kimura, Tomoo Saga, Toshimitsu Annaka, Shingo Yamada, Li Zhao, Shengqi Li, Arata Azuma, Akihiko Gemma, Shoji Kudoh, Ke

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

2010

Language:

english

File:

PDF, 447 KB

english, 2010

30

Direct determination of MUC5B promoter haplotypes based on the method of single-strand conformation polymorphism and their statistical estimation

Koichiro Kamio, Ikumi Matsushita, Goh Tanaka, Jun Ohashi, Minako Hijikata, Koh Nakata, Katsushi Tokunaga, Arata Azuma, Shoji Kudoh, Naoto Keicho

Journal:

Year:

2004

Language:

english

File:

PDF, 337 KB

english, 2004

31

Fine Localization of a Major Disease-Susceptibility Locus for Diffuse Panbronchiolitis

Naoto Keicho, Jun Ohashi, Gen Tamiya, Koichiro Nakata, Yoshio Taguchi, Arata Azuma, Nobuya Ohishi, Mitsuru Emi, Myoung Hee Park, Hidetoshi Inoko, Katsushi Tokunaga, Shoji Kudoh

Journal:

The American Journal of Human Genetics

Year:

2000

Language:

english

File:

PDF, 216 KB

english, 2000

32

The safety and efficacy of weekly paclitaxel in combination with carboplatin for advanced non-small cell lung cancer with idiopathic interstitial pneumonias

Minegishi, Yuji, Sudoh, Junko, Kuribayasi, Hideaki, Mizutani, Hideki, Seike, Masahiro, Azuma, Arata, Yoshimura, Akinobu, Kudoh, Shoji, Gemma, Akihiko

Journal:

Year:

2011

Language:

english

File:

PDF, 214 KB

english, 2011

33

Reply 2

Enomoto, Tatsuji, Sugisaki, Midori, Kamio, Koichiro, Azuma, Arata

Journal:

Year:

2013

Language:

english

File:

PDF, 111 KB

english, 2013

34

EM703 improves bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-β signaling in lung fibroblasts

Ying Ji Li, Arata Azuma, Jiro Usuki, Shinji Abe, Kuniko Matsuda, Toshiaki Sunazuka, Takako Shimizu, Yukiyo Hirata, Hirofumi Inagaki, Tomoyuki Kawada, Satoru Takahashi, Shoji Kudoh, Satoshi Omura

Journal:

Respiratory Research

Year:

2006

Language:

english

File:

PDF, 3.95 MB

english, 2006

35

Sub-speciation of Mycobacterium tuberculosis complex from tuberculosis patients in Japan

Ueyama, Masako, Chikamatsu, Kinuyo, Aono, Akio, Murase, Yoshiro, Kuse, Naoyuki, Morimoto, Kozo, Okumura, Masao, Yoshiyama, Takashi, Ogata, Hideo, Yoshimori, Kozo, Kudoh, Shoji, Azuma, Arata, Gemma, Ak

Journal:

Year:

2014

Language:

english

File:

PDF, 315 KB

english, 2014

36

Pirfenidone inhibits fibrocyte accumulation in the lungs in bleomycin-induced murine pulmonary fibrosis

Inomata, Minoru, Kamio, Koichiro, Azuma, Arata, Matsuda, Kuniko, Kokuho, Nariaki, Miura, Yukiko, Hayashi, Hiroki, Nei, Takahito, Fujita, Kazue, Saito, Yoshinobu, Gemma, Akihiko

Journal:

Respiratory Research

Year:

2014

Language:

english

File:

PDF, 1.62 MB

english, 2014

37

INHALATION OF DIESEL EXHAUST FOR THREE MONTHS AFFECTS MAJOR CYTOKINE EXPRESSION AND INDUCES BRONCHUS-ASSOCIATED LYMPHOID TISSUE FORMATION IN MURINE LUNGS

Hiramatsu, Kumiko, Azuma, Arata, Kudoh, Shoji, Desaki, Masashi, Takizawa, Hajime, Sugawara, Isamu

Journal:

Experimental Lung Research

Year:

2003

Language:

english

File:

PDF, 2.07 MB

english, 2003

38

EM, EM703 inhibit NF-kB activation induced by oxidative stress from diesel exhaust particle in human bronchial epithelial cells: Importance in IL-8 transcription

Li, Ying-Ji, Shimizu, Takako, Hirata, Yukiyo, Inagaki, Hirofumi, Takizawa, Hajime, Azuma, Arata, Kawada, Tomoyuki, Sugawara, Isamu, Kudoh, Shoji, Sunazuka, Toshiaki, Omura, Satoshi

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2013

Language:

english

File:

PDF, 442 KB

english, 2013

39

Consensus statement for the diagnosis and treatment of drug-induced lung injuries

Kubo, Keishi, Azuma, Arata, Kanazawa, Minoru, Kameda, Hideto, Kusumoto, Masahiko, Genma, Akihiko, Saijo, Yasuo, Sakai, Fumikazu, Sugiyama, Yukihiko, Tatsumi, Koichiro, Dohi, Makoto, Tokuda, Hitoshi, H

Journal:

Respiratory Investigation

Year:

2013

Language:

english

File:

PDF, 1.73 MB

english, 2013

40

411 Hypothalamic and cortical histamine release in vivo under constant dark condition

Mochizuki, Takatoshi, Okakura-Mochizuki, Kaori, Horii, Arata, Yamamoto, Yumiko, Azuma, Hitoshi, Yamatodani, Atsushi

Journal:

Neuroscience Research Supplements

Year:

1993

Language:

english

File:

PDF, 97 KB

english, 1993

41

Clinical features, anti-cancer treatments and outcomes of lung cancer patients with combined pulmonary fibrosis and emphysema

Minegishi, Yuji, Kokuho, Nariaki, Miura, Yukiko, Matsumoto, Masaru, Miyanaga, Akihiko, Noro, Rintaro, Saito, Yoshinobu, Seike, Masahiro, Kubota, Kaoru, Azuma, Arata, Kida, Kouzui, Gemma, Akihiko

Journal:

Year:

2014

Language:

english

File:

PDF, 582 KB

english, 2014

42

Double-blind controlled trial of lecithinized superoxide dismutase in patients with idiopathic interstitial pneumonia – short term evaluation of safety and tolerability

Kamio, Koichiro, Azuma, Arata, Ohta, Ken, Sugiyama, Yukihiko, Nukiwa, Toshihiro, Kudoh, Shoji, Mizushima, Tohru

Journal:

BMC Pulmonary Medicine

Year:

2014

Language:

english

File:

PDF, 283 KB

english, 2014

43

The use of macrolides in the 2009 H1N1 virus infection outbreak: A survey of general practices in Japan

Azuma, Arata, Yamaya, Mutsuo, Kadota, Jun-ichi, Mikasa, Keiichi, Kudoh, Shoji

Journal:

Respiratory Investigation

Year:

2013

Language:

english

File:

PDF, 296 KB

english, 2013

44

Diagnostic Values For Club Cell Secretory Protein (CC16) in Serum of Patients of Combined Pulmonary Fibrosis and Emphysema

Kokuho, Nariaki, Ishii, Takeo, Kamio, Koichiro, Hayashi, Hiroki, Kurahara, Misuzu, Hattori, Kumiko, Motegi, Takashi, Azuma, Arata, Gemma, Akihiko, Kida, Kozui

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Year:

2014

Language:

english

File:

PDF, 2.21 MB

english, 2014

45

Double-blind, Placebo-controlled Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis

Azuma, Arata, Nukiwa, Toshihiro, Tsuboi, Eiyasu, Suga, Moritaka, Abe, Shosaku, Nakata, Koichiro, Taguchi, Yoshio, Nagai, Sonoko, Itoh, Harumi, Ohi, Motoharu, Sato, Atsuhiko, Kudoh, Shoji

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2005

Language:

english

File:

PDF, 399 KB

english, 2005

46

[IEEE 2008 IEEE Asian Solid-State Circuits Conference (A-SSCC) - Fukuoka, Japan (2008.11.3-2008.11.5)] 2008 IEEE Asian Solid-State Circuits Conference - 1.25Gbps optical links for mobile handsets

Shin'ichiro Azuma,, Ryoji Yanagimoto,, Shingo Kamitani,, Masakazu Edamoto,, Katsumi Arata,, Hirofumi Matsui,, Hiroyuki Akada,, Ryoichi Masuda,, Kozo Hoshino,, Kazuhito Nagura,, Hiroaki Ogawa

Year:

2008

Language:

english

File:

PDF, 218 KB

english, 2008

47

Promoter Analysis and Aberrant Expression of the MUC5B Gene in Diffuse Panbronchiolitis

Kamio, Koichiro, Matsushita, Ikumi, Hijikata, Minako, Kobashi, Yoichiro, Tanaka, Goh, Nakata, Koh, Ishida, Takafumi, Tokunaga, Katsushi, Taguchi, Yoshio, Homma, Sakae, Nakata, Koichiro, Azuma, Arata,

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2005

Language:

english

File:

PDF, 1.57 MB

english, 2005

48

EM703, A NEW DERIVATIVE OF ERYTHROMYCIN, INHIBITS TRANSFORMING GRWTH FACTOR-β SIGNALING IN HUMAN LUNG FIBROBLASTS

Yu, ChangHe, Azuma, Arata, Li, YingJi, Wang, Chunyan, Abe, Sinji, Usuki, Jiro, Matsuda, Kuniko, Kudoh, Shoji, Sunazuka, Toshiaki, Omura, Satoshi

Journal:

Experimental Lung Research

Year:

2008

Language:

english

File:

PDF, 1.04 MB

english, 2008

49

AIRWAY INFLAMMATORY RESPONSES TO OXIDATIVE STRESS INDUCED BY LOW-DOSE DIESEL EXHAUST PARTICLE EXPOSURE DIFFER BETWEEN MOUSE STRAINS

Li, Ying-Ji, Kawada, Tomoyuki, Matsumoto, Aki, Azuma, Arata, Kudoh, Shoji, Takizawa, Hajime, Sugawara, Isamu

Journal:

Experimental Lung Research

Year:

2007

Language:

english

File:

PDF, 1.04 MB

english, 2007

50

LONG-TERM INHALATION OF DIESEL EXHAUST AFFECTS CYTOKINE EXPRESSION IN MURINE LUNG TISSUES: COMPARISON BETWEEN LOW- AND HIGH-DOSE DIESEL EXHAUST EXPOSURE

Saito, Yoshinobu, Azuma, Arata, Kudo, Shoji, Takizawa, Hajime, Sugawara, Isamu

Journal:

Experimental Lung Research

Year:

2002

Language:

english

File:

PDF, 517 KB

english, 2002

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